By Bhanu P. Chowdhary
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Supported by the Arbeitsgemeinschaft Deutscher Rinderzüchter (German cattle breeders federation, ADR) and the Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research, BMBF, project 0311020A). E. F. as part of the “Bioinformatics for the Functional Analysis of Mammalian Genomes” (BFAM) project. Received 28 May 2003; manuscript accepted 1 August 2003. com © 2003 S. 50/0 Copyright © 2003 S. com/cgr DGAT2 and its relatives encode intrinsic membrane proteins that are completely unrelated to DGAT1.
Gautier M, Hayes H, Eggen A: A comprehensive radiation hybrid map of bovine chromosome 26 (BTA26): comparative chromosomal organization between HSA10q and BTA26 and BTA28. Mammal Genome 14: in press (2003). Georges M, Andersson L: Livestock genomics comes of age. Genome Res 6:907–921 (1996). Goss SJ, Harris H: New method for mapping genes in human chromosomes. Nature 255:680–684 (1975). Gu Z, Womack JE, Kirkpatrick BW: Synteny mapping of four genes from the short arm of human chromosome 19 to bovine chromosome 7.
2003) using the same procedure. It should also be noticed that these ratios are concordant with those based on genetic distances. 05 cM (previous results for BTA15 and BTA26 lead to a similar ratio). Assuming that 1 cM corresponds to about 1 Mb (in a first approximation we neglect cold and hot spots since we are considering the entire chromosome), this gives a ratio 1 cR3000 for 50 kb. These two independent methods of estimating correspondence between radiation hybrid distance and physical dis- tance are thus concordant although their calculation is based on strong hypothesis.