Atlas of CSF cytology by Harald Kluge

By Harald Kluge

A whole, single-volume reference for the cytological exam of
cerebrospinal fluid!

This full-color atlas offers the entire crucial
information wanted for achieving a correct cytological analysis of
cerebrospinal fluid and its abnormalities. Designed as a medical and laboratory
reference, Atlas of CSF Cytology offers an outline of all of the average
diagnostic suggestions and gives perception into complex equipment corresponding to stream
cytometry and immunocytological phenotyping. short descriptions of the
indications, benefits, and barriers are supplied for every process. An
extensive number of greater than three hundred high quality cytological images
demonstrating basic mobilephone buildings, in addition to pathological cells in acute and
remission levels allows the reader to appreciate affliction processes.


  • Guidelines for the correct dealing with of specimens, phone coaching, and marking
  • Review of the typical resources of mistakes in prognosis
  • Thorough insurance of the strategies for detecting and classifying inflammatory,
    infectious, neoplastic, and hemorrhagic stipulations of the imperative anxious procedure
  • Descriptions of the main good points of cells and the class of tumor
    cell forms in response to present W.H.O. criteria
  • Full-color photos depicting pathological adjustments of CSF cells -- an imperative visible relief to

Atlas of CSF Cytology is perfect for experts in neurology,
neurosurgery, pathology/neuropathology, cytopathology, microbiology, and
laboratory drugs, in addition to for these internists, pediatricians, and
psychiatrists who often request cytological exam of the CSF. although
it is written to fulfill the wishes of experts, the "Atlas" may also be chanced on
accessible and enlightening by means of scientific scholars, interns and

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Extra resources for Atlas of CSF cytology

Example text

Fig. 6 Polynuclear initial phase of bacterial meningitis. In the center is a granulocyte with phagocytosed diplococci. Granulocyte hypersegmentation indicates toxic cell damage. 27 with transitional, premalignant forms, and for their distinction from individual, reactive giant cells, see also Chapter 5. Thieme-Verlag Frau Langner 28 Sommer-Druck Feuchtwangen Kluge et al. 2006 Chapter-3 3 Pathological CSF Cell Findings in Infectious and Inflammatory Diseases of the Central Nervous System Fig. 7 Bacterial meningitis in the early remission phase.

Neurosyphilis is associated with a mixed picture, mainly mononuclear (lymphocytes, activated lymphocytes, plasma cells), but consisting of rare granulocytes as well. Mixed pictures with lymphocytic predominance are also found in a number of rarer diseases— neurobrucellosis, leptospirosis, Legionnaires disease, CNS infection with Mycoplasma pneumoniae, and Whipple disease. ), the early CSF picture may be either mainly granulocytic or mixed, with activated lymphocytes and plasma cells. In the chronic stage, lymphocytes predominate.

The cell picture contains hypersegmented granulocytes, most of which are already altered, as well as two plasma cells and a plasma cell progenitor (arrow) with a hyperchromatic nucleus and marked cytoplasmic basophilia. Fig. 28 Viral meningoencephalitis of unknown etiology with large numbers of mononuclear cells, some of which manifest dispersion (breaking up) of their nucleus and cytoplasm. Other findings include hypersegmented granulocytes and lymphocytes in various stages of activation. Thieme-Verlag Frau Langner Sommer-Druck Feuchtwangen Kluge et al.

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