By Dhammika Amaratunga
This publication offers an outstanding evaluation of varied equipment in DNA microarray research. It explains many of the theories in the back of the algorithms, so you understand why the analyses are performed in convinced means. in reality, i locate i am getting extra insights from the e-book as examine to the study papers which are typically short.
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Additional info for Exploration and Analysis of DNA Microarray and Protein Array Data
Example text
This triggers fluorescence in the tagged samples, which causes a signal to be passed through the optical fiber to a detector, which indicates which probe DNA sequences match some sequence in the labeled sample. The throughput of three-dimensional bead-based microarrays is a great deal higher than conventional two-dimensional microarrays. In fact the number of DNA sequences tested could be in the hundreds of thousands, or even millions, range. 7 CONFIRMATION OF MICROARRAY RESULTS Microarray technology is still a dynamic and evolving entity.
In bioinformatics, scientists in the biological and computational sciences, together with significant contributions from other disciplines, collaborate to provide insight into biological processes. Statistics is an essential component of many of these activities. As a fledgling discipline, bioinformatics does not yet have a well-defined charter, but some common bioinformatics activities are given below. Creution and Maintenance of Databases. As a first step, the magnitude and complexity of the data being collected has led to the creation of large relational databases to store, organize, and index such data.
As such, the state of the technology at this time is that microarray experimental results could be rather variable. , 2002). Thus the key is to utilize microarrays as a means of screening and prioritizing a large number of genes, but any findings pertaining to genes of special interest should be independently confirmed. This is generally done on a gene-by-gene basis using methods such as Northern blots or quantitative RT-PCR. SUPPLEMENTARY READING AND ELECTRONIC REFERENCES 1. Animations. The Web sites http: //m.