Generic and Specific Roles of Saccharides at Cell and by Emanuel Schneck

By Emanuel Schneck

Systematic investigations of the constitution, mechanics, and dynamics of organic surfaces aid us comprehend extra approximately organic strategies occurring at cellphone and micro organism surfaces. provided here's a research of the position membrane-bound saccharides play within the modulation of interactions among cells/bacteria and their environments. during this thesis, membrane buildings have been probed perpendicular and parallel to the outside, and complicated planar versions of biomembranes composed of glycolipids of varied structural complexities have been designed. additionally, specular and off-specular X-ray and neutron scattering experiments have been performed. This learn has ended in the improvement of a number of new equipment for extracting info at the constitution and mechanics of saccharide-rendered biomembranes from the measured scattering signs. in truth, extra is referred to now in regards to the impression of the saccharide constitution. those effects display that the research of planar version structures with X-ray and neutron scattering thoughts gives you entire perception into the constitution and mechanics of advanced organic surfaces.

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L. Névot, P. Croce, Characterization of surfaces by grazing X-ray reflection––application to the study of polishing of some silicate glasses. Rev. Phys. Appl. 15, 761 (1980) 49. G. Parratt, Surface studies of solids by total reflection of X-rays. Phys. Rev. 95, 359 (1954) 50. F. Abelès, Recherches théoriques sur les propriétés optiques des lames minces. J. Phys. Rad. 11, 307 (1950) 51. V. Nitz, M. -P. H. Seeck, J. Stettner, W. Press, M. Stelzle, E. Sackmann, Correlations in the interface structure of Langmuir–Blodgett films observed by Xray scattering.

This is illustrated in Fig. 8. Solid-supported lipid monolayers can be created by spreading small unilamellar lipid vesicles (SUVs) onto hydrophobic solid substrates under bulk buffer. The formation of the monolayer is driven by the hydrophobic effect. The resulting in-plane density of lipid molecules is very similar to that found in lipid bilayer membranes. Alternative methods for the deposition of lipid monolayers onto hydrophobic substrates are the Langmuir– Blodgett or Langmuir–Schaefer transfer [29], which enable the control of the in-plane density of the lipids.

C ðr Þ :¼ u ! r0 À ! r Áu ! r0 ! r 0  À Á À Á Cnm ðx; yÞ ! Cnm ðr Þ :¼ un ! r Á um ! r0 À ! r0 ! r 0 with r ¼ j! rj An example of such a radial symmetric height–height correlation function is shown in Fig. 2. 3 Membrane Displacement Correlation Functions In analogy, a statistical, time-averaged description of the fluctuations of interacting membranes is provided by the membrane displacement correlation functions DÂ À Á À ÁÃ 2 E gnm ðr Þ :¼ un ! : r À um ! r0 À ! r0 ! r 0 Lei et al. have derived an expression [54] which is valid in the special case of oriented multilayers that are infinitely expanded in all directions.

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