Integrating the Neurobiology of Schizophrenia by Anissa Abi-Dargham

By Anissa Abi-Dargham

This e-book examines the position that dopamine performs in schizophrenia, reading its function in not just the indicators of the ailment but additionally in its remedy. It additionally reports all neurotransmitters which have been implicated in schizophrenia, exploring the genetic info, medical information implicating the transmitter, and the preclinical information exploring how a transmitter may perhaps have interaction with dopamine and give a contribution to the dopaminergic phenotype saw within the disease. This publication will function an instructional device for teachers, a advisor for clinicians, and be of curiosity to researchers. it's a solid reference for researchers really expert in a single specific region and drawn to studying approximately different parts of pathology in schizophrenia and the way they could all feed into one another. The e-book concludes with an total integrative version assembling as lots of those components as attainable.

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Lieberman, J. , Kane, J. , and RamosLorenzi, J. (1987b). Prediction of relapse in schizophrenia. Arch. Gen. Psychiatry 44, 597–603. Lieberman, J. , Kinon, B. , and Loebel, A. D. (1990). Dopaminergic mechanisms in idiopathic and drug-induced psychoses. Schizophr. Bull. 16, 97–110. Lieberman, J. , Sheitman, B. , and Kinon, B. J. (1997). Neurochemical sensitization in the pathophysiology of schizophrenia: Deficits and dysfunction in neuronal regulation and plasticity. Neuropsychopharmacology 17, 205–229.

2004). Presynaptic dopaminergic dysfunction in medicated schizophrenic patients. Arch. Gen. Psychiatry 61, 134–142. Meador-WoodruV, J. , Damask, S. , Davis, K. , and Watson, S. J. (1996). Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology 15, 17–29. , and Gessa, G. L. (1999). Clozapine potently stimulates mesocortical dopamine neurons. Eur. J. Pharmacol. 366, R11–R13. , Miletich, R. , Kohn, P. , Carson, R. , Weinberger, D. , and Berman, K. F. (2002). Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia.

Hoover, J. , and Strick, P. L. (1993). Multiple output channels in the basal ganglia. Science 259, 819–821. Hsiao, M. , Lin, K. , Liu, C. , Tzen, K. , and Yen, T. C. (2003). Dopamine transporter change in drug-naive schizophrenia: An imaging study with 99mTc-TRODAT-1. Schizophr. Res. 65, 39–46. , Fowler, W. , O’Laughlin, I. , and Meltzer, H. Y. (2001). 5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: A possible mechanism of atypical antipsychotic-induced cortical dopamine release.

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