Nutritional Bioavailability of Manganese by Constance Keys

By Constance Keys

content material: Manganese bioavailability assessment / Constance Kies --
Manganese uptake and retention : experimental animal and human stories / Bo Lönnerdal, Carl L. prepared, J.G. Bell, and B. Sandström --
nutritional manganese toxicity and deficiency : results on mobile manganese metabolism / Carl L. willing, Sheri Zidenberg-Cherr, and Bo Lönnerdal --
Manganese homeostasis within the chick / L. Lee Southern, David H. Baker, and Kevin M. Halpin --
function of manganese in bone metabolism / Linda Strause and Paul Saltman --
greater tissue lipid peroxidation : mechanism underlying pathologies linked to nutritional manganese deficiency / Sheri Zidenberg-Cherr and Carl L. prepared --
Iron in manganese metabolism / N. Gruden --
Absorption reports of manganese from milk diets in suckling rats / Wai-Yee Chan, M. Hassan Raghib, and Owen M. Rennert --
Manganese requisites of people / Jeanne H. Freeland-Graves, Connie W. Bales, and Fares Behmardi --
Manganese metabolism in epilepsy : basic or irregular? / G.F. Carl, Carl L. willing, B.B. Gallagher, and L.S. Hurley --
Plasma uptake of manganese : impression of nutritional components / Connie W. Bales, Jeanne H. Freeland-Graves, Pao-Hwa Lin, Jan M. Stone, and Virginia Dougherty --
Manganese and lipid metabolism as plagued by nutritional manganese and fats / Jan M. Johnson and Constance Kies --
Manganese availability for people : influence of chosen nutritional elements / Constance Kies, K.D. Aldrich, Jan M. Johnson, C. Creps, C. Kowalski, and R.H. Wang --
Manganese utilization in people as suffering from use of calcium supplementations / Susan D. McDermott and Constance Kies.

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The tissue distribution of Mn orally administered to mice was followed. Specific Mn(II) binding site characterized usin months, dietary regimens depleted in Mn or low Mn-low Cu showed significantly lower bone density and higher serum Ca than controls. The application of ectopic subcutaneous implants of bone powder and demineralized bone powder into animals on control or Mn deplete diets demonstrated that osteoblast activity, a measure of bone formation, was impaired as was osteoclast activity, a parameter of bone resorption.

Excess dietary Mn reduces Fe u t i l i z a t i o n , but excess Fe does not affect Mn utilization. Eimeria acervulina infection increases Mn absorption. Manganese n u t r i t u r e o f t h e c h i c k has been a f e r t i l e area o f i n v e s t i g a t i o n f o r over 50 y e a r s . Wilgus and a s s o c i a t e s (1) i n 1936 r e p o r t e d t h a t Mn would prevent p e r o s i s i n c h i c k s . Numerous r e s e a r c h p u b l i c a t i o n s have s i n c e expanded t h e knowledge o f Mn homeostasis i n t h e c h i c k .

Lee Southern, David H. Baker, and Kevin M. Halpin 2,3 1 Department of Animal Science, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge, LA 70803 Department of Animal Sciences, University of Illinois, Urbana, IL 61801 2 Manganese is a nutritionally important trace element for chicks. Dietary energy and protein sources contain very little bioavailable Mn, and these feed ingredients reduce the biopotency of inorganic Mn supplements exerted primaril reduced Mn absorption and is mediated by the fiber and/or ash components of the feedstuffs.

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