By Joint FAO/WHO Expert Committee on Food Additives. Meeting; World Health Organization.; International Program on Chemical Safety
Read Online or Download Safety evaluation of certain food additives PDF
Similar nonfiction_7 books
Fluorescence in Bio-inspired Nanotechnology: First as Probe, Then as Function
In his thesis Fluorescence in Bio-inspired Nanotechnology, Jonas Hannestad describes the evolving box of DNA nanotechnology in a lucid and simply obtainable means. A relevant topic within the thesis is how organic buildings and mechanisms represent a foundation for the layout of novel applied sciences. Hannestad discusses how self-assembled, nanometer-scale DNA constructs will be functionalized utilizing fluorescent labeling.
Additional info for Safety evaluation of certain food additives
Sample text
In deriving the ADI for cyclamates, it was assumed that 37% was absorbed in the body and not metabolized. 9%). Applying the conversion rate factor and the ratio of molecular weights for cyclamate and cyclohexylamine of 2 to the NOAEL for cyclohexylamine of 100 mg/kg bw per day resulted in a calculated NOAEL for cyclamates of 1058 mg/kg bw per day. A safety factor of 100 was assumed to derive the ADI of 0–11 mg/kg bw for cyclamates. 2, respectively. CYCLAMIC ACID AND ITS SALTS: DIETARY EXPOSURE ASSESSMENT 31 New data on the metabolism of cyclamates in humans have been published since the twenty-sixth meeting of JECFA.
Applying the conversion rate factor and the ratio of molecular weights for cyclamate and cyclohexylamine of 2 to the NOAEL for cyclohexylamine of 100 mg/kg bw per day resulted in a calculated NOAEL for cyclamates of 1058 mg/kg bw per day. A safety factor of 100 was assumed to derive the ADI of 0–11 mg/kg bw for cyclamates. 2, respectively. CYCLAMIC ACID AND ITS SALTS: DIETARY EXPOSURE ASSESSMENT 31 New data on the metabolism of cyclamates in humans have been published since the twenty-sixth meeting of JECFA.
4 in the EU (250 mg/l) and in Australia and New Zealand (350 mg/kg) and in nectars in the Codex GSFA (400 mg/kg), it is necessary to use other sweeteners in conjunction with cyclamates in these products to achieve complete sugar replacement and the desired sweetness profile. 4 containing 12% sugar, assuming a relative sweetness of 30. 4. 1 Concentrations of cyclamates in food In most dietary exposure assessments, it has been assumed that cyclamates are present in the food either at the maximum use level as permitted in the relevant food legislation or at typical use levels as reported by manufacturers.