By Tie-Hua Ng
Take Your NI Trial to the following Level
Reflecting the huge examine on noninferiority (NI) designs from the prior 15 years, Noninferiority checking out in medical Trials: concerns and Challenges explains the right way to pick out the NI margin as a small fraction of the healing influence of the energetic regulate in a scientific trial. Requiring no earlier wisdom of NI trying out, the e-book is well obtainable to either statisticians and nonstatisticians fascinated about drug development.
With over two decades of expertise during this quarter, the writer introduces the elemental parts of the NI trials separately in a logical order. He discusses matters with estimating the impression measurement in line with ancient placebo keep an eye on trials of the lively keep an eye on. The e-book covers basic techniques on the topic of NI trials, akin to assay sensitivity, fidelity assumption, discounting, and upkeep. It additionally describes sufferer populations, three-arm trials, and the equivalence of 3 or extra groups.
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Additional resources for Noninferiority Testing in Clinical Trials: Issues and Challenges
Example text
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